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皮质纹状体脊髓变性,即克-雅氏病(Creutzfeldt-Jakob Disease,CJD)又称亚急性海绵体脑病(subacute spongiform encephalopathy,SSE),是一种由朊病毒(prions)感染引起的、以大脑皮层、基底节、小脑和脊髓神经细胞变性脱失和胶质细胞海绵状增生为主的朊病毒病。1920年creutzfeldt首次报道一例该病,此后国内外有数百例报道。我们试就宣武医院最近5年诊治的6例作一分析。 1 临床资料 1.1一般情况:6例均为住院病人,其中男4例,女2例,年龄31～62岁(51.2±11.5岁),病程50天～4个月(2.83±0.98月);职业:农民3人,工人1人,工程师1人,医生1人;既往史:1例有冠心
Corticospinal spinal cord degeneration, Creutzfeldt-Jakob Disease (CJD), also known as subacute spongiform encephalopathy (SSE), is a prion-causing infection caused by Cerebral cortex, basal ganglia, cerebellar and spinal cord degeneration and degeneration of nerve cells and glial sponge-like proliferation of prion diseases. Creutzfeldt first reported a case of the disease in 1920, since there are hundreds of reports at home and abroad. We try Xuanwu Hospital in the past five years for diagnosis and treatment of 6 cases for an analysis. 1 clinical data 1.1 General situation: 6 cases were hospitalized patients, including 4 males and 2 females, aged 31 to 62 years (51.2 ± 11.5 years), duration of 50 days to 4 months (2.83 ± 0.98 months); occupation : 3 peasants, 1 workers, 1 engineer, 1 doctor; Past history: 1 case of coronary heart