论文部分内容阅读
目的调查温州地区无偿献血者人类疱疹病毒8型(HHV-8)和人类巨细胞病毒(HCMV)感染情况,为制定预防策略提供依据。方法采用ELISA法检测无偿献血者血浆HHV-8 Ig G和HCMV-Ig G抗体,并分析HHV-8 Ig G和HCMV-Ig G阳性率与人口学特征的关系。结果 273名无偿献血者的HHV-8 Ig G抗体阳性率为14.65%,465名无偿献血者的HCMV-Ig G抗体阳性率为24.09%。不同年龄、文化程度和职业献血者的HHV-8 Ig G阳性率差异无统计学意义(P>0.05),HCMV-Ig G阳性率差异有统计学意义(P<0.05)。44~55岁、初中及以下文化、工人/农民HCMV-Ig G阳性率相对较高。结论温州地区无偿献血者中存在一定比例的HHV-8和HCMV感染,建议增加相关筛查,特别是高龄、低文化程度和工人/农民职业人群。
Objective To investigate the prevalence of human herpesvirus type 8 (HHV-8) and human cytomegalovirus (HCMV) infection in non-compensation blood donors in Wenzhou area, and to provide the basis for the development of prevention strategies. Methods The plasma levels of HHV-8 Ig G and HCMV-Ig G were measured by ELISA. The relationship between the positive rate of HHV-8 Ig G and HCMV-Ig G and the demographic characteristics was analyzed. Results The positive rate of HHV-8 Ig G antibody in 273 blood donors was 14.65%. The positive rate of HCMV-Ig G antibody in 465 blood donors was 24.09%. There was no significant difference in the positive rate of HHV-8 Ig G among different age, educational level and occupational blood donors (P> 0.05). The positive rate of HCMV-Ig G was statistically significant (P <0.05). 44-55 years old, junior high school and below culture, worker / farmer HCMV-Ig G positive rate is relatively high. Conclusions There is a certain proportion of HHV-8 and HCMV infection among unpaid blood donors in Wenzhou area, and it is suggested to increase relevant screening, especially for senior citizens, people with lower education level and occupational workers / peasants population.