抗甲状腺药物、手术和放射性碘是目前治疗Graves病的三大主要方法。由于药物疗法具有方法简便、安全有效、不造成永久性甲低等优点,所以最易为病人接受。近年来发现,Graves病有自愈倾向,其自然缓解率约为20～30％,进一步增加了甲亢病人首选抗甲状腺药物治疗的合理性。但大量临床观察表明,经药物治疗病情稳定后,即使常规生化检查证实病人的甲功已恢复正常,停药后随访,50～70％,终将复发,复发时间大多(70～80％)在停药后12个月内。无疑,准确判断能否复发对决定 Antithyroid drugs, surgery and radioactive iodine are the three main methods currently used to treat Graves disease. Because drug therapy has the method of simple, safe and effective, does not cause a permanent advantage, so the most easy for patients to accept. In recent years found that Graves disease has a tendency to self-healing, the natural remission rate of about 20 to 30%, further increasing the rational choice of anti-thyroid drugs for patients with hyperthyroidism. However, a large number of clinical observations show that after the drug treatment is stable, even if the routine biochemical examination confirmed that the patient’s thyroid function has returned to normal, 50 to 70% of the patients were followed up after stopping the drug treatment. The recurrence will eventually occur with the recurrence time mostly ranging from 70 to 80% Within 12 months after discontinuation. Undoubtedly, the exact judge whether the recurrence of the decision