急性冠脉综合征(ACS)发病机制主要为冠脉内动脉粥样硬化斑块不稳定、破裂而导致血小板聚集形成血栓。而斑块破裂和血栓形成取决于斑块的易损性(vulnerability),血管新生是斑块易损性的一个重要危险因素[1]。血流切应力异常被认为是易损斑块形成的重要原因[2]。但迄今为止,有关 The main pathogenesis of acute coronary syndrome (ACS) is coronary atherosclerotic plaque instability, rupture and lead to platelet aggregation thrombosis. Plaque rupture and thrombosis depend on the vulnerability of the plaque, an important risk factor for plaque vulnerability [1]. Abnormal blood flow shear stress is considered an important cause of vulnerable plaque [2]. But so far, related