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笔者于1984年2月至1992年10月用静脉滴注硫酸镁与硝酸甘油治疗急性心梗泵衰竭(以下称心衰)13例,获得较满意疗效。报告如下: 1 临床资料 本组性别:男9例,女4例。年龄:最小42岁,最大68岁。 心衰类型:急性前间壁心梗5例,急性广泛前壁心梗6例,急性下壁心梗2例。13例中均有轻重不同的肺瘀血或/和肺水肿征,并有体循环瘀血征。心功能(NYHA)Ⅲ9例,(NYHA)Ⅳ4例。顽固性水肿者10例,有体循环灌注不全但血压正常者3例。13例中并发室早7例,长期低血钾3例。 本组病例均为经限盐、应用利尿剂、钙离子拮抗剂及血管紧张素转换酶抑制治疗无效或效果不显著者。血清镁低于1.25mEq/L11例,正常者2例。 2 治疗方法 在上述治疗方法基础上增添25％硫酸镁10～20ml,硝酸甘油10～30mg加入5～10％葡萄糖液250ml中静滴,每日一次,每分钟10～20滴,5～10天为一疗程。用药过程中注意观察血压及尿量。 3 治疗结果 经治疗的13例中11例有效,占84.6％。其中显效(心慌心悸明显好转,胸闷气短消失,尿量增加,浮
The author in February 1984 to October 1992 with intravenous infusion of magnesium sulfate and nitroglycerin in the treatment of acute myocardial infarction failure (hereinafter referred to as heart failure) in 13 cases, to obtain more satisfactory results. The report is as follows: 1 Clinical data The gender of this group: 9 males and 4 females. Age: minimum 42 years old, maximum 68 years old. Type of heart failure: acute anterior myocardial infarction in 5 cases, acute extensive anterior myocardial infarction in 6 cases, acute inferior myocardial infarction in 2 cases. Thirteen cases of different severity of pulmonary blood stasis or / and pulmonary edema sign, and systemic blood stasis syndrome. Heart function (NYHA) Ⅲ 9 cases, (NYHA) Ⅳ 4 cases. 10 cases of intractable edema, systemic insufficiency but normal blood pressure in 3 cases. In 13 cases, 7 cases were complicated as early as in room and 3 cases were long-term hypokalemia. This group of patients are limited salt, the application of diuretics, calcium antagonists and angiotensin converting enzyme inhibition of ineffective treatment or no significant effect. Serum magnesium less than 1.25mEq / L11 cases, 2 cases of normal. 2 treatment on the basis of the above treatment by adding 25% magnesium sulfate 10 ~ 20ml, nitroglycerin 10 ~ 30mg 5 ~ 10% glucose solution 250ml intravenous infusion once daily, 10 to 20 drops per minute, 5 to 10 days For a course of treatment. Pay attention to observe the blood pressure and urine output during medication. 3 treatment results in 13 cases of 13 cases were effective, accounting for 84.6%. Which markedly (palpitation palpitations significantly improved, shortness of breath shortness of breath disappeared, increased urine output, floating