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目的探讨川芎嗪联合口服匹多莫德佐治小儿哮喘疗效。方法 73例住院患儿随机分为治疗组(n=35)和对照组(n=38),对照组给予常规治疗,治疗组在常规治疗的基础上给予匹多莫德和川穹嗪联合治疗,观察比较治疗前后患儿哮喘治疗效果、血液淋巴细胞亚群检测结果及TGF-β1水平等指标。结果治疗组总有效率为94.29%,明显高于对照组(P<0.01),血清IgA、IgG、IgM、TGF-β1及T细胞亚群与对照组比较具有统计学差异(P<0.01)。结论匹多莫德联合川穹嗪治疗儿童支气管哮喘具有良好的临床疗效。
Objective To investigate the curative effect of ligustrazine and oral pidotimod on children asthma. Methods A total of 73 hospitalized children were randomly divided into treatment group (n = 35) and control group (n = 38). The control group was given routine treatment. The treatment group was given pidotimod and The therapeutic effect of asthma in children with asthma and blood lymphocyte subsets and TGF-β1 levels were observed and compared before and after treatment. Results The total effective rate of the treatment group was 94.29%, which was significantly higher than that of the control group (P <0.01). The serum IgA, IgG, IgM, TGF-β1 and T cell subsets were significantly different from the control group (P <0.01). Conclusion Pidotimod combined with actopanadine in children with bronchial asthma has a good clinical effect.