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作者对小剂量阿斯匹林改善不孕症患者IVF预后的作用进行了前瞻性，随机双官对照研究，298例患者随机分为治疗组（149例）和对照组（149例），两组患者平均年龄分别为35．9±4．2岁和354±39岁。治疗组患者从前一周期的第21天开始每日服用阿斯匹林IO0mg，对照组应用安慰剂。所有患者从前一月经周期的黄体中期开始给予IuPronms／天进行垂体脱敏，E。＜99．gPmol／L时，改为ling／天直至hCG注射日，同时用FSH或hCG超促排卵。微粒化孕酮3O0mg川阴道用药和孕酮10Omg周肌肉注射支持黄体。前一周期的第二天和超促排卵周期MG注射日阴道彩色多普勒超声测定子宫和卵巢血流速度表示为搏动指数（PI），同时观察卵巢反应性指标。结果显示：两组的胚胎移植数最少为2个，平均3．3个（2～5个）。治疗组和对照组hCG注射日直径＞15rum的卵泡数分别为19．8土7．2和Ic．2土5．3。回收卵子数分别为16．2土67和8．6士4．6；hCG注射日血EZ水平分别为I（）818·O6士3786．58Pmol／L和5972．9土2929．29Prnol／L，上述三项指标均相差显著。治疗组的取消周期比率明显低于对照组，分别为4％和9％，治疗组和对照组的种植率分别为17．8％和92％，临床妊娠率分别为45％和28％，相差显著。与前一周期第2天相比，治疗组患者hCG注射日子宫
The authors conducted a prospective, randomized double-blind, controlled study of the effect of low-dose aspirin in improving IVF outcomes in infertile patients. 298 patients were randomly divided into treatment group (149 cases) and control group (149 cases) The average patient age was 35.9 ± 4.2 years and 354 ± 39 years, respectively. Patients in the treatment group took aspirin 10 mg daily from day 21 of the previous cycle and placebo in the control group. All patients were given IuPronms / day for pituitary desensitization starting from the mid-luteal phase of the previous menstrual cycle, E. <99. gPmol / L, to ling / day until hCG injection day, while using FSH or hCG ovulation hyperactivity. Micronized progesterone 3O0mg Chuan vaginal medication and progesterone 10Omg weekly intramuscular injection of luteal support. On the second day of the previous cycle and vaginal ultra-ovulation cycle, MG vaginal color Doppler ultrasound measured uterine and ovarian blood flow velocities were expressed as pulsatility index (PI) while observing ovarian response. The results showed that: the two groups of embryo transfer number of at least 2, an average of 3.3 (2 to 5). The number of follicles in the treatment group and the control group with a diameter> 15 mm on the day of hCG injection were 19.8 ± 7.2 and 1 cm, respectively. 2 dirt 5.3. The number of recovered eggs were 16.2 ± 67 and 8.6 ± 4.6, respectively; the levels of EZ on the day of hCG injection were I () 818 · O6 ± 3786.58Pmol / L and 5972.9 ± 2929.29Prnol / L respectively, The above three indicators are significant differences. The cancellation cycle rate of the treatment group was significantly lower than that of the control group (4% and 9% respectively). The implantation rates of the treatment group and the control group were 17.8% and 92% respectively, and the clinical pregnancy rates were 45% and 28% Significant. In the treatment group, hCG was injected into the uterus on day 2 compared to day 2 of the previous cycle