淀粉样变为一全身性疾病,尸解发病率国内报道为0.25～0.28％,国外报道为0.4～0.5％。肾淀粉样变系由淀粉样物质沉积于肾脏引起。一、病因肾淀粉样变病因分五类:(1)原发性者病因不明,无诱发病,病变主要侵犯心血管、消化道、脾、肝、肾、皮肤及神经系统,肾受累者占40％。(2)继发性者多继发于慢性感染,如结核、肺化脓症、支气管扩张、慢性骨髓炎、梅毒以及类风湿关节炎、系统性红斑狼疮、糖尿病、干燥综合征、多发性肌炎、硬皮病、牛皮癣、白塞氏病、溃疡性结肠炎等。病变主要侵犯肾、脾、肝及肾上腺等,肾受累者占80％。(3)并发于多发性骨髓瘤及其他恶性肿瘤,如何杰金 Amyloidosis into a systemic disease, the incidence of autopsy in the country for the 0.25 to 0.28%, foreign reports of 0.4 to 0.5%. Renal amyloidosis is caused by the deposition of amyloid in the kidneys. First, the etiology of renal amyloidosis etiology divided into five categories: (1) primary etiology is unknown, no evoked disease, the lesion mainly affects the cardiovascular, gastrointestinal, spleen, liver, kidney, skin and nervous system, kidney involvement 40%. (2) secondary to secondary secondary to chronic infections such as tuberculosis, pulmonary effusion, bronchiectasis, chronic osteomyelitis, syphilis and rheumatoid arthritis, systemic lupus erythematosus, diabetes, Sjogren’s syndrome, polymyositis , Scleroderma, psoriasis, Behcet’s disease, ulcerative colitis and the like. Lesions mainly infringe the kidney, spleen, liver and adrenal glands, kidney involvement accounted for 80%. (3) complicated by multiple myeloma and other malignancies, how Jie Jin