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清栓酶(蛇毒抗栓酶,Ancrod)自1963年由Reid首次提取以来,作为去纤剂巳逐步应用于临床。国内自1982年以来先后有多篇报道清栓酶对脑血栓有良好疗效。但上述报道均夫进行双盲对照,未能排除血栓性疾病的自愈性及其他因素对疗效的影响。本科自1989年10月至1990年3月用双盲法观察清检酶的临床疗效,现将结果报道如下。 资料与方法 本组脑梗塞病人共18例(包括脑血栓形成15例,腔隙性脑梗塞3例),均为发病4天以内的急性期颈内动脉系统梗塞病人,符
Qing-thrombin (snake venom antithrombin, Ancrod) since 1963 was first extracted by Reid has been gradually applied as a defibrillator clinically. Domestic since 1982, there have been many reports of Qing thrombin on cerebral thrombosis have a good effect. However, the above reports were double-blind control, failed to rule out the self-healing thrombotic disease and other factors on the effect. Undergraduate from October 1989 to March 1990 double-blind observation of clinical efficacy of enzyme clearance, the results are reported below. Materials and Methods A total of 18 patients with cerebral infarction in this group (including 15 cases of cerebral thrombosis, lacunar infarction in 3 cases), are within 4 days of acute carotid artery infarction patients,