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目的研究分析广州地区人群骨密度(BMD)变化规律及骨质疏松(OP)的发病率,为骨质疏松防治提供依据。方法采用美国GE-Lunar公司生产的Prodigy型双能X线骨密度仪,分别测试4 152例20~100岁受试者的L1-4及股骨上段的骨密度(BMD)值。按照年龄、性别进行不同分组,以10岁为1个年龄段。结果随着年龄增加骨量减少发生率不断增加,由15.5%增加到最高49.4%,在60岁以上年龄组增加不明显;其中50~60岁各年龄组女性骨量减少明显高于同组男性。骨质疏松发生率在50岁以上各年龄组骨质疏松发生率增加明显,由7.6%增加到最高33.7%,在70岁以上各年龄组增加最高,女性明显高于同组男性。结论骨密度随年龄增长而下降,骨量减少和骨质疏松发病率也随之增加;同年龄组女性发病率明显高于男性。出现骨量减少时应及时治疗,以免进一步发展为不可逆转骨质疏松症。
Objective To study the changes of bone mineral density (BMD) and the incidence of osteoporosis (OP) in Guangzhou population and provide evidence for the prevention and treatment of osteoporosis. Methods The BMD of L1-4 and the upper femur of 4 152 patients aged 20 to 100 years were measured by Prodigy dual-energy X-ray absorptiometry (GE-Lunar). According to age, sex, different groups, to 10 years of age for an age. Results The incidence of osteopenia increased with the increase of age from 15.5% to 49.4%, but not significant in the age group of over 60 years old. The bone mass loss in all age groups of 50-60 years old was significantly higher than that of the same group of men . The incidence of osteoporosis in all age groups over the age of 50 significantly increased the incidence of osteoporosis, from 7.6% to the highest 33.7%, the highest increase in all age groups over the age of 70, women were significantly higher than the same group of men. Conclusion BMD decreased with age, and the incidence of osteopenia and osteoporosis also increased. The incidence of female in the same age group was significantly higher than that of male. In the event of bone loss should be promptly treated, so as not to further develop into irreversible osteoporosis.