应用母体血中胎儿细胞进行产前诊断可避免对母儿的创伤,有利于样本采集。现在许多工作都用于分离极少量的胎儿细胞,主要为胎儿有核红细胞,但对稀少的胎儿细胞进行基因型的分型也十分重要。目前,荧光PCR是一种相对便宜且敏感的诊断手段,该法可较广泛地用于检测单基因缺陷和/或非整倍体病。它已应用于包括单细胞的植入前诊断等 Prenatal diagnosis of fetal cells using maternal blood can prevent the trauma to maternal and child, is conducive to the sample collection. Much of the work now is devoted to separating very small amounts of fetal cells, primarily fetal erythroblasts, but genotyping of rare fetal cells is also important. Currently, fluorescent PCR is a relatively inexpensive and sensitive diagnostic tool that can be used more broadly to detect single-gene defects and / or aneuploidy. It has been used in preimplantation diagnostics including single cells