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肼苯哒嗪除其体循环作用外,尚可在原发性或继发性肺动脉高压患者降低其静息或运动时的肺小动脉阻力.作者曾在数例患者中见到,虽然用肼苯哒嗪后肺血管阻力降低而肺动脉压无改变,但其右心衰竭的症状和体征均有所减轻,类似肼苯哒嗪在血压正常的左心室衰竭中的作用——尽管体循环血压几乎无改变,心排出量增加而左心室充盈降低.为了阐明血管扩张剂对右心室功能的作用,本文在14例肺动脉高压、右心室衰竭的患者,评价肼苯达嗪的效应.方法:14名单纯右心衰竭患者,肺动脉高压的原因包括房间隔或室间隔缺损,原发性肺动脉高压,
In addition to its body circulation, hydralazine can reduce pulmonary arteriolar resistance at rest or during exercise in patients with primary or secondary pulmonary hypertension. The authors have seen in several patients that hydrazinobenzene Pyridazine decreased pulmonary vascular resistance and pulmonary arterial pressure without change, but the right heart failure symptoms and signs were reduced, similar to hydralazine in normotensive left ventricular failure role - despite little change in systemic blood pressure , Cardiac output increased and left ventricular filling decreased.In order to elucidate the role of vasodilators on right ventricular function, this article in 14 cases of pulmonary hypertension, right ventricular failure, evaluation of hydralazine effect.Methods: Causes of heart failure in patients with pulmonary hypertension include atrial septal or ventricular septal defect, primary pulmonary hypertension,