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目的探讨前列腺癌(PCa)和良性前列腺增生(BPH)患者红细胞分布宽度(RDW)的差异。方法回顾性分析877例经直肠前列腺穿刺活检患者的RDW值,比较PCa组(385例)和BPH组(492例)患者RDW值的差异。绘制ROC曲线确定RDW诊断PCa的最佳界值,比较不同RDW值的穿刺阳性率。结果 PCa组患者RDW值为(13.34±1.24)%,高于BPH组的(12.78±0.64)%(P<0.01)。取13.05%作为诊断PCa的界值,RDW值>13.05%和≤13.05%穿刺患者的前列腺穿刺阳性率分别为59.3%和32.6%(P<0.01)。结论 RDW可能是PCa的一种预测因素,RDW值>13.05%时前列腺穿刺活检的阳性率增加。
Objective To investigate the difference of erythrocyte distribution width (RDW) in patients with prostate cancer (PCa) and benign prostatic hyperplasia (BPH). Methods The RDW of 877 patients who underwent transrectal prostatic biopsy was retrospectively analyzed. The differences of RDW between PCa group (385 cases) and BPH group (492 cases) were compared. ROC curve was drawn to determine the best cutoff value of RDa for diagnosing PCa, and the positive rate of different RDWs was compared. Results The RDW in PCa group was (13.34 ± 1.24)%, which was higher than that in BPH group (12.78 ± 0.64)% (P <0.01). The positive rate of prostatic puncture in patients with RDW> 13.05% and ≤13.05% was 59.3% and 32.6% (P <0.01), respectively. Conclusions RDW may be a predictor of PCa. The positive rate of biopsy of prostate biopsy increased with RDW> 13.05%.