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1988～1992年广西八个地区23所医院连续五年共监测围产儿106041例,出生缺陷儿1157例,出生缺陷总发生率为10.91‰,较1986～1987年12.96‰明显下降(X~2=13.3686,P<0.01),农村出生缺陷率13.01‰高于城镇9.18‰(X~2=35.7742,P<0.01);多胎出生缺陷34.55‰高于单胎10.68‰(X~2=52.9625,P<0.01);单一畸形755例占65.25％。多胎畸形103例占8.9％,胎儿水肿综合征299例占10.69％。结果提示由于围产保健网建立,产科质量不断提高,围产儿出生缺陷率在下降。
From 1988 to 1992, 23 hospitals in eight districts of Guangxi Province monitored 106,041 perinatal births and 1157 birth defects in a row over the past five years. The total incidence of birth defects was 10.91 ‰, which was significantly lower than that from 1986 to 1987 (X 2 = 13.3686, P <0.01). The birth defect rate in rural areas was 13.01 ‰ higher than that in urban areas (X 2 = 35.7742, P 0.01). The incidence of multiple birth defects was 34.55 ‰ higher than that of single embryos 10.68 ‰ (X 2 = 52.9625, P < 0.01); single deformity 755 cases accounted for 65.25%. 103 cases of multiple malformations accounted for 8.9%, 299 cases of fetal edema syndrome accounted for 10.69%. The results suggest that due to the establishment of perinatal health care network, the quality of obstetrics continues to increase, and the rate of birth defects in perinatal children is declining.