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目的：探讨茵陈蒿汤醇提物的保肝作用与肿瘤坏死因子（ＴＮＦ）的关系。方法：ＴＮＦ以ＭＴＴ法检测。结果：茵陈蒿汤醇提物０２～２０μｇ直接加入小鼠腹腔巨噬细胞培养液可抑制ＴＮＦ的释放；血清药理学表明含茵陈蒿汤醇提物小鼠血清１００、１５０、２００、２５０ｍｉｎ对ＴＮＦ也有抑制作用，且有时效关系，效应高峰在２００ｍｉｎ。结论：茵陈蒿汤醇提物保肝途径之一是调节巨噬细胞释放ＴＮＦ的功能
Objective: To investigate the relationship between liver protection and tumor necrosis factor (TNF) in alcohol extracts of Yinchenhao decoction. Methods: TNF was detected by MTT assay. RESULTS: The alcohol extract of Yinchenhao Tang was added directly to the mouse peritoneal macrophage medium to inhibit the release of TNF. The serum pharmacology showed that the alcohol extracts of Yinchenhao Tang contained mouse serum 100, 150, 200 250min also had inhibitory effect on TNF with a time-dependent relationship. The peak effect was 200min. Conclusion: One of the hepatoprotective methods of Yin Chen Hao Tang alcohol extract is to regulate the function of macrophage to release TNF