重症哮喘是支气管哮喘的一种致命的疾病状态。我院对常规综合治疗无效的20例患者,加用酚妥拉明静滴疗效满意,报道如下。 1.临床资料 患者男12例,女8例,年龄17～63岁,平均34岁。哮喘病史最长25年,最短7年,咳喘持续时间最短24小时,最长96小时。 治疗方法 均住院,吸氧、平喘类药物如茶碱类、β_2受体激动剂并与糖皮激素联合应用,给予强力广谱抗生素,常规补液等对症治疗,哮喘未获控制后加用酚妥拉明静滴。用量10mg加入5％葡萄糖250ml中滴注,从每分钟16滴开始,视病情及治疗效果调整滴速,一般16～ Severe asthma is a deadly condition of bronchial asthma. 20 patients in our hospital routine conventional treatment ineffective, plus phentolamine intravenous infusion of satisfactory results are reported below. 1 clinical data of 12 males and 8 females, aged 17 to 63 years, mean 34 years. A history of asthma up to 25 years, the shortest 7 years, the shortest duration of cough and asthma 24 hours, up to 96 hours. Methods of treatment were hospitalized, oxygen, asthma drugs such as theophylline, β 2 receptor agonist and glucocorticoid combined with strong antibiotics given, such as conventional rehydration symptomatic treatment of asthma without control after the addition of phenol Toramide intravenous infusion. Dosage 10mg add 5% glucose in 250ml instillation, starting from 16 drops per minute, depending on the condition and treatment effect to adjust the drip rate, usually 16 ~