目的　研究维生素C赖氨酸的肝损伤保护作用。方法　采用小鼠四氯化碳肝损伤和小鼠乙醇肝损伤动物模型。结果　四氯化碳肝损伤中 ,维生素C赖氨酸 30 0 ,6 0 0 ,1 2 0 0mg·kg- 1 口服给药 3天可剂量依赖性的逆转血清SOD的降低 ,并且6 0 0mg·kg- 1 给药组可明显降低四氯化碳造成的血清AST ,ALT和LDH水平的升高。同样的 ,维生素C赖氨酸 30 0 ,6 0 0 ,1 2 0 0mg·kg- 1 口服给药 3天可剂量依赖性的降低由过量乙醇造成的血清甘油三酯的升高。结论　上述结果显示 ,维生素C赖氨酸不仅结构上有别于单纯的维生素C和赖氨酸 ,其还有一定的肝损伤保护作用 Objective To study the protective effect of vitamin C lysine on liver injury. Methods CCl 4 -induced liver injury and alcohol-induced liver injury were induced in mice. Results CCl 4 liver injury, vitamin C lysine 300, 600, 120 mg · kg-1 oral administration of 3 days dose-dependent reversal of serum SOD decreased, and 600 mg · kg- kg-1 administration group can significantly reduce the carbon tetrachloride caused by serum AST, ALT and LDH levels increased. Similarly, oral administration of vitamin C lysine at 30 0, 60, 120 mg · kg -1 for 3 days dose-dependently reduced elevated serum triglycerides caused by excess ethanol. Conclusion The above results show that vitamin C lysine is not only structurally distinct from vitamin C and lysine alone, but also protects against liver injury