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晚期卵巢癌标准治疗方案为初次肿瘤细胞减灭术和以铂类为基础的联合化疗。但仍有70%的患者复发。复发卵巢癌姑息治疗的目的是控制疾病相关症状、降低治疗的副反应,延长生存期,延迟病情进展的时间,维持或更好地提高生存质量。这些患者常需要二次肿瘤细胞减灭术及二线化疗。世界各地学者做了许多努力来寻求适宜的复发卵巢癌化疗方案,包括各种方法的单独及联合使用。现就近年来国内外复发卵巢癌联合化疗的效果研究予以综述。
The standard treatment for advanced ovarian cancer is initial cytoreductive surgery and platinum-based combination chemotherapy. However, 70% of patients still relapse. The purpose of palliative treatment of recurrent ovarian cancer is to control disease-related symptoms, reduce the side effects of treatment, prolong survival, delay the progression of the disease, maintain or improve the quality of life. These patients often require secondary cytoreductive surgery and second-line chemotherapy. Scholars around the world have made a number of efforts to find suitable chemotherapy regimens for recurrent ovarian cancer, including the use of various methods, both alone and in combination. Now on the domestic and international recurrence of ovarian cancer combined with chemotherapy are reviewed.