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体内生成的一氧化氮(NO)有广泛的生物学作用.吸入NO 对肺血管有选择性舒张作用,能对抗缺氧性肺血管收缩,已用于治疗新生儿肺动脉高压、与心脏病有关的肺动脉高压和成人呼吸窘迫综合征。吸入有效浓度时毒副作用不明显.
Nitric oxide (NO) produced in vivo has a wide range of biological effects. Inhaled NO selectively regulates pulmonary vasoconstriction against hypoxic pulmonary vasoconstriction and has been used to treat neonatal pulmonary hypertension and is associated with heart disease Pulmonary hypertension and adult respiratory distress syndrome. Inhalation effective concentration of toxic side effects are not obvious.