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目的：探讨皮下埋植式给药装置在口腔癌化疗中应用的可行性及效果。方法：采用国产ＭＴ埋植式给药装置（ＩＤＤＳ）对２２例口腔癌患者的２６侧颈外动脉插管，连接皮下埋植式给药装置，术后经皮穿刺进行动脉灌注化疗，观察局部和全身反应以及肿瘤治疗效果。结果：经３～１９个月体内保留给药装置的多周期联合用药化疗，证实该装置使用方便，疗效好，无明显全身及局部毒副作用。结论：ＩＤＤＳ是口腔癌患者化疗方法的最佳选择之一，可作为多药物、多周期单一化疗、同一患者术前诱导及术后辅助化疗、化疗联合放疗等综合治疗的给药途径，具有推广应用价值。
Objective: To investigate the feasibility and effect of subcutaneous implantable device in oral cancer chemotherapy. METHODS: Twenty-six external carotid arteries of 22 patients with oral cancer were cannulated with a domestic MT implantable device (IDDS). The subcutaneous implanted device was used to connect with the skin. Percutaneous puncture was performed after arterial infusion chemotherapy. And systemic reaction and tumor treatment effect. RESULTS: After 3 to 19 months of in-vivo administration of the drug delivery device to the multi-cycle combination chemotherapy, it was confirmed that the device is easy to use, effective, and has no significant systemic or local toxic side effects. Conclusion: IDDS is one of the best choices of chemotherapy for oral cancer patients. It can be used as a multi-drug, multi-cycle single chemotherapy, preoperative induction of the same patient, postoperative adjuvant chemotherapy, chemotherapy and radiotherapy, etc. Value.