A meso-scale truss network model was developed to predict chloride diffusion in concrete. The model regards concrete as a three-phase composite of mortar matrix, coarse aggregates, and the interfacial transition zone (ITZ) between the mortar matrix and the aggregates. The diffusion coefficient of chloride in the mortar and the ITZ can be analytically determined with only the water-to-cement ratio and volume fraction of fine aggregates. Fick’s second law of diffusion was used as the governing equation for chloride diffusion in a homogenous medium (e.g., mortar); it was discretized and applied to the truss network model. The solution procedure of the truss network model based on the diffusion law and the meso-scale composite structure of concrete is outlined. Additionally, the dependence of the diffusion coefficient of chloride in the mortar and the ITZ on exposure duration and temperature is taken into account to illustrate their effect on chloride diffusion coefficient. The numerical results show that the exposure duration and environmental temperature play important roles in the diffusion rate of chloride ions in concrete. It is also concluded that the meso-scale truss network model can be applied to chloride transport analysis of damaged (or cracked) concrete. A meso-scale truss network model was developed to predict chloride diffusion in concrete. The model regards concrete as a three-phase composite of abrasive matrix, coarse aggregates, and the interfacial transition zone (ITZ) between the mortar matrix and the aggregates. The The diffusion coefficient of chloride in the mortar and the ITZ can be analytically determined with only the water-to-cement ratio and volume fraction of fine aggregates. Fick’s second law of diffusion was used as the governing equation for chloride diffusion in a homogenous medium (eg , and mortar); it was discretized and applied to the truss network model. The solution procedure of the truss network model based on the diffusion law and the meso-scale composite structure of concrete is outlined. additional, the dependence of the diffusion coefficient of chloride In the mortar and the ITZ on exposure duration and temperature is taken into account to illustrate their effect on chloride diffusion coefficient. The numerical Results show that the exposure duration and environmental temperature play important roles in the diffusion rate of chloride ions in concrete. It is also concluded that the meso-scale truss network model can be applied to chloride transport analysis of damaged (or cracked) concrete.