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目的观察沙丁胺醇溶液、布地奈德氧气驱动雾化吸入治疗毛细支气管炎的疗效。方法将临床确诊毛细支气管炎患儿96例,随机分为两组。治疗组48例(沙丁胺醇及布地奈德雾化吸入组)和对照组48例(地塞米松静脉滴注)。观察用药前后患儿症状、体征(咳嗽、喘憋、哮鸣音、肺部湿啰音等)消失时间及住院日。结果两组均未发现与药物明显相关的不良反应,治疗组显效率明显高于对照组,差异有统计学意义。结论沙丁胺醇、布地奈德联合氧气驱动雾化吸入治疗毛细支气管炎有协同作用,可以明显改善症状及缩短病程,提高治愈率,避免全身使用激素所产生的不良反应。
Objective To observe the curative effect of salbutamol solution and budesonide oxygen driven atomization inhalation on bronchiolitis. Methods 96 patients with bronchiolitis diagnosed clinically were randomly divided into two groups. In the treatment group, 48 cases (salbutamol and budesonide inhalation group) and 48 cases (dexamethasone intravenous drip). Observed before and after treatment of children with symptoms, signs (cough, wheezing, wheezing, lung wet rales, etc.) disappear time and hospitalization days. Results No adverse reactions were found in the two groups. The effective rate of the treatment group was significantly higher than that of the control group, the difference was statistically significant. Conclusions Salbutamol and budesonide combined with oxygen-driven atomization inhalation have a synergistic effect on bronchiolitis, which can significantly improve the symptoms and shorten the course of the disease, improve the cure rate and avoid adverse reactions caused by systemic hormones.