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老年糖尿病患者的生理学特点,决定了他们在选择治疗药物时有其自身的特点。二甲双胍是首选的一线降糖药物;二代磺脲类药物较一代药物更为安全,在老年人中应用广泛;α-葡萄糖苷酶抑制剂和非磺脲类促泌剂有利于降低餐后血糖;老年人应用胰岛素应注意避免低血糖事件。新的降糖药物肠促胰素样物质更为安全,能减少低血糖等不良反应。老年患者的治疗应循序渐进,治疗目标需适度放宽。
Physiological characteristics of elderly patients with diabetes, they decided to choose the treatment of drugs has its own characteristics. Metformin is the preferred first-line hypoglycemic drug; second-generation sulfonylureas are safer than the first-generation drugs and are widely used in the elderly; alpha-glucosidase inhibitors and non-sulfonylurea secretagogues help reduce postprandial blood glucose The elderly should be taken to avoid insulin hypoglycemia. The new hypoglycemic drugs, incretin-like substance is more secure, can reduce adverse reactions such as hypoglycemia. The treatment of elderly patients should be gradual, the treatment target needs to be moderately relaxed.