活心丹是治疗冠心病、心绞痛、心肌缺血及心功能不全的中成药。临床疗效确切。本文通过实验表明,活心丹能显著地降低家兔全血和血浆的比粘度,使纤维蛋白原减少。但对细胞电泳率无显著影响。毒性试验表明,小鼠腹腔注射活心丹供试液,经计算LD_(50)为518.42±10.4mg/kg,提示该药安全性较大。 Huoxindan is a proprietary Chinese medicine for the treatment of coronary heart disease, angina pectoris, myocardial ischemia, and cardiac insufficiency. Clinical efficacy is exact. This experiment shows that Huoxindan can significantly reduce the rabbit’s whole blood and plasma specific viscosity and reduce fibrinogen. However, there was no significant effect on the electrophoretic rate of the cells. The toxicity test showed that the mice were intraperitoneally injected with Huoxuedan test solution. The calculated LD_(50) was 518.42±10.4mg/kg, indicating that the drug was safer.