贾第虫病是一种常见的寄生虫病,成人和儿童都能感染。患者可因急性腹泻,而导致吸收障碍或严重脱水。但其流行区内有的感染者不出现症状。虽已提出许多贾第虫病的可能病因,如毒素分泌、炎症、上皮细胞损害以及重复感染等,但对其毒性的确切机理尚不明了。一旦供水系统被污染,就有可能发生社镇范围的暴发性贾第虫病。新近发现在男性同性恋者间传播,一些日托托儿站的发病数亦在渐增。本文作者介绍了各种药物治疗贾第虫病的疗效、副作用及其可能出现的致癌性,以供医生用药时的参考。 Giardiasis is a common parasitic disease that can be infected both in adults and children. Patients may suffer from malabsorption or severe dehydration due to acute diarrhea. However, some infected persons in the endemic areas showed no symptoms. Although many possible causes of giardiasis have been proposed, such as toxin secretion, inflammation, epithelial cell damage and repeated infections, the precise mechanism of toxicity is unknown. Once the water system is contaminated, outbreaks of Giardiasis in the community are likely to occur. Recently, it has been reported among homosexual men and the number of daily nurseries has also been increasing. The authors describe the efficacy, side effects and potential carcinogenicity of various drugs for the treatment of giardiasis for reference by physicians.