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采用 TAD 方案治疗急性非淋巴细胞性白血病(ANLL)12例,年龄17～47岁。总有效率为66.7%,完全缓解率(CR)为41.7%。5例获 CR 的时间是26～66天,平均53天,较国内其它方案为快。CR 时间为2～9月,平均6.2月,较其它方案又较短。TAD 方案对心脏的毒性作用轻微。TAD 方案对5例获 CR 者,于诱导治疗第一疗程后,除1例外,骨髓中白血病细胞百分比下降均不明显;但于第二疗程后,白血病细胞全部减少到骨髓有核细胞总数的20%/以下,这种现象似可作为本方案预后的观察指标。
TAD program for the treatment of acute non-lymphocytic leukemia (ANLL) in 12 cases, aged 17 to 47 years. The total effective rate was 66.7% and the complete response rate (CR) was 41.7%. 5 cases of CR time is 26 to 66 days, an average of 53 days, faster than other programs in China. CR time for 2 to 9 months, an average of 6.2 months, compared with other programs and shorter. The TAD regimen has a mild effect on the heart. TAD program on 5 cases of CR patients, after induction of the first course of treatment, with the exception of one exception, the percentage of bone marrow leukemia decreased not; but after the second course of leukemia cells were reduced to the total number of bone marrow cells 20 % / Below, this phenomenon seems to be the prognostic indicator of the program.