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目的观察低分子量肝素治疗不稳定型心绞痛(UA)的临床疗效。方法治疗组采用常规治疗+低分子量肝素腹部皮下注射,对照组采用硝酸酯类、钙离子拮抗剂、β-受体阻滞剂和阿司匹林等药物常规治疗。结果治疗组与对照组治疗UA的总有效率分别为92.3%和71.1%,两组治疗后疗效比较差异有统计学意义(P<0.05)。结论加用低分子量肝素治疗UA优于常规疗法,且安全性好,无明显不良反应。
Objective To observe the clinical effect of low molecular weight heparin in the treatment of unstable angina pectoris (UA). Methods The patients in the treatment group were given routine treatment and subcutaneous injection of low molecular weight heparin. The control group was treated with nitrates, calcium antagonists, β-blockers and aspirin. Results The total effective rates of treatment UA in treatment group and control group were 92.3% and 71.1%, respectively. There was significant difference between the two groups after treatment (P <0.05). Conclusion Addition of low molecular weight heparin is superior to conventional therapy in treating UA with good safety and no obvious adverse reactions.