解脲支原体(UU)是生育期妇女生殖道最常见病原菌之一。UU感染在新生儿尤其是早产儿中感染比例逐年增高。近年来发现UU感染后,促使炎症细胞因子表达,加重炎症反应,干扰炎症清除,而与早产、低出生体质量、支气管肺发育不良、慢性肺疾病、呼吸窘迫综合征等多种围生期疾病有关。红霉素、阿奇霉素、肺表面活性物质、糖皮质激素等对UU感染疾病的治疗尚有争议。 Ureaplasma urealyticum (UU) is one of the most common pathogenic bacteria in the reproductive tract of women during the reproductive period. UU infection in newborns, especially premature children, the proportion of infections increased year by year. In recent years, UU infection was found to promote the expression of inflammatory cytokines, exacerbate the inflammatory response, interfere with the clearance of inflammation, but with a variety of perinatal diseases such as preterm birth, low birth weight, bronchopulmonary dysplasia, chronic lung disease and respiratory distress syndrome related. Erythromycin, azithromycin, pulmonary surfactant, glucocorticoids and other diseases on the treatment of UU is still controversial.