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收集分析了子宫颈神经内分泌癌 8例 ,其中 ,Ⅰa期 1例 ;Ⅰb期 2例 ;Ⅱa期 2例 ;Ⅱb期 1例 ;Ⅲa期 1例 ;Ⅲb期 1例。3例进行了广泛子宫切除及盆腔淋巴结清扫术 ,5例进行了放射治疗。5例死亡前分别存活 13~38个月 ,平均 19个月。仍存活的 3例分别为治疗后3、4、5个月 ,其中 1例已发生肾转移。结果提示 ,子宫颈小细胞神经内分泌癌是一种罕见的子宫颈恶性程度高的肿瘤 ,易发生早期转移 ,预后差 ;早期病例应采取广泛子宫及盆腔淋巴结清扫术 ,并进行放疗或化疗。晚期病例只能行化疗或放射治疗。
Eight cases of cervical neuroendocrine carcinoma were collected and analyzed. Among them, there were 1 case of stage Ⅰa, 2 cases of stage Ⅰb, 2 cases of stage Ⅱ a, 1 stage of stage Ⅱb, 1 stage of stage Ⅲa and 1 stage of stage Ⅲb. Three patients underwent extensive hysterectomy and pelvic lymphadenectomy, and five patients underwent radiotherapy. Five patients survived before the death of 13 to 38 months, an average of 19 months. Three cases were still alive after 3, 4, 5 months after treatment, of which 1 had renal metastases. The results suggest that cervical intracellular small cell neuroendocrine cancer is a rare high degree of cervical cancer, prone to early metastasis, the prognosis is poor; early cases should take extensive uterine and pelvic lymph node dissection, and radiotherapy or chemotherapy. Late cases can only be treated with chemotherapy or radiation therapy.