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目的探讨抗血小板药物在治疗冠心病合并糖尿病中的应用价值。方法冠心病合并糖尿病患者60例随机分为观察组和对照组,各30例。对照组采用常规的药物治疗,包括控制血糖、应用硝酸酯剂、β受体阻滞剂等;观察组在常规治疗的基础上同时应用阿司匹林100 mg/d。根据两组患者的心脏缺血事件发生率和血管超声检查结果评价两组患者的治疗效果。结果对照组发生心脏缺血事件15例,其中住院10例,斑块脂质含量(70.74±11.82)mmol/L;观察组发生心脏缺血事件6例,其中住院3例,斑块脂质含量(50.45±11.58)mmol/L,两组比较差异有统计学意义(P<0.05)。结论阿司匹林治疗冠心病合并糖尿病疗效显著,能预防心脏缺血事件的发生,降低斑块脂质含量。
Objective To investigate the value of antiplatelet drugs in the treatment of coronary heart disease complicated with diabetes mellitus. Methods Sixty coronary heart disease patients with diabetes mellitus were randomly divided into observation group and control group, with 30 cases in each group. The control group used routine drug therapy, including the control of blood glucose, nitrates, beta blockers, etc .; the observation group on the basis of conventional treatment with aspirin 100 mg / d. According to the two groups of patients with cardiac ischemic event rate and vascular ultrasound examination results to evaluate the treatment effect of two groups of patients. Results In the control group, there were 15 cases of cardiac ischemic events, including 10 hospitalized patients with plaque lipid (70.74 ± 11.82) mmol / L; 6 cases of ischemic events in the observation group, including 3 hospitalized patients, plaque lipid content (50.45 ± 11.58) mmol / L, the difference between the two groups was statistically significant (P <0.05). Conclusion Aspirin treatment of coronary heart disease with diabetes significantly effect, can prevent the occurrence of cardiac ischemic events, reduce plaque lipid content.