血管内皮细胞抑制素(血管内皮抑素)是近年发现的具有抑制新生血管形成作用的蛋白质,表现出强烈的抑瘤作用;p53是公认的抑癌基因。本文就两者的功能、应用等方面作一综述。近年,抗肿瘤血管和转基因治疗越来越成为治疗肿瘤的两大生力军。肿瘤的生长、浸润及转移依赖血管供氧、营 Vascular Endostatin (Endostatin) is a protein that has been found to inhibit neovascularization in recent years and shows a strong anti-tumor effect. P53 is a well-known tumor suppressor gene. This article reviews the functions and applications of both. In recent years, anti-tumor blood vessels and transgenic treatment are increasingly becoming the two major force in the treatment of cancer. Tumor growth, invasion and metastasis rely on vascular oxygen supply, camp