新城疫病毒的分类及治疗胶质瘤研究的进展

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脑胶质瘤是人类中枢神经系统中最常见的原发恶性肿瘤,因其致残率、致死率高而被国内外学者广泛研究。传统的手术、放疗及化疗等治疗手段并不能达到满意的治疗效果。近些年各种生物基因治疗不断涌现,其中溶瘤病毒的抗肿瘤作用正在引起学者的广泛关注和研究,新城疫病毒( NDV)的胶质瘤治疗更是研究的热点。现就NDV的发现、溶瘤的结构基础、分类及关于治疗胶质瘤的研究及反向遗传技术的应用等进行总结。
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