在肾移植中,习惯上将群体反应性抗体(PRA)阳性的受者称为致敏受者。这些受者体内往往存在针对供体的特异性抗体(DSA),包括HLA-Ⅰ,Ⅱ类抗体和一些非HLA类的抗体,是移植术后排斥的高危人群。受者术前体内如果预存大量的DSA,术后会立即引起超急性排斥,直接导致移植肾丢失。即使预 In kidney transplants, recipients who are accustomed to positive for group-reactive antibodies (PRA) are referred to as sensitized recipients. These recipients often have donor-specific antibodies (DSA), including HLA class I, class II antibodies and some non-HLA class antibodies, which are at high risk of rejection after transplantation. Recipients who preoperatively pre-save a large number of DSA, the surgery will immediately lead to hyperacute rejection, a direct result of graft loss. Even pre-