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花椒(Z.bungeanum Max)果实含挥发油(柠檬烯、枯醇、香叶醇等)、甾醇、不饱和有机酸。除具有温中、散寒、驱虫和止痒功能外,据报道尚有局部麻醉作用。我们应用电生理实验技术,观察了花椒对蟾蜍离体坐骨神经冲动的传导和兴奋性的影响。方法取干燥成熟花椒果皮按1:10比例浸泡于任氏(Ringer)液(一种用于两栖类动物的生理盐溶液)中,24小时后,其浸出液(下称花椒浸液)供实验用。制备蟾蜍坐骨神经标本,把神经标本置于
The Z. bungeanum Max fruit contains volatile oils (limonene, cumyl alcohol, geraniol, etc.), sterols, and unsaturated organic acids. In addition to its function of warming, cooling, repelling and relieving itching, local anesthetic effects have also been reported. We applied electrophysiological experiments to observe the effect of Zanthoxylum bungeanum on the conduction and excitability of isolated sciatic nerve impulses. Methods The dry mature pepper peel was soaked in Ringer’s solution (a physiological salt solution for amphibians) in a ratio of 1:10. After 24 hours, the leachate (hereinafter referred to as the pepper extract) was used for experiments. . Prepare sciatic nerve specimens and place the nerve specimens