非酒精性脂肪肝(ＮＡＳＨ)作为儿童慢性肝病的常见原因正日益引起重视,ＮＡＳＨ与肥胖有关,组织学改变为小疱及大疱样脂肪变性,伴门静脉周围炎症及桥联纤维化。唯一治疗方法是减肥,作者应用维生素Ｅ(ＶｉｔＥ)抗氧化治疗转氨酶增高但无其他肝病的肥胖儿童。方法１９９７年６月~１９９９年１月对年龄８~１６岁、血清谷草转氨酶(ＡＳＴ)及谷丙转氨酶(ＡＬＴ)增高超过３个月,肥胖,而且肝脏超声检查、病史、体检及实验室检查均未见有可损害肝 Non-alcoholic fatty liver (NASH) is a common cause of chronic liver disease in children is increasingly attention, NASH and obesity, histological changes to small blisters and bullous steatosis, with portal vein inflammation and bridging fibrosis. The only treatment is to lose weight, the authors apply vitamin E (VitE) anti-oxidant treatment of elevated transaminases but no other liver disease in obese children. Methods From June 1997 to January 1999, the serum levels of AST and ALT were increased more than 3 months, obese, and liver ultrasound examination, medical history, physical examination and laboratory examination Have seen no damage to the liver