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目的 :为了早期、准确地判定急性缺血性心肌损伤程度。方法 :采用酶联免疫吸附方法 ,对 41例急性心肌梗塞患者、 38例心绞痛 (AP)疑有微小心肌损伤 (MMD)患者以及 40例健康 (HP)人进行心脏肌钙蛋白 T(c Tn T)测定 ,同时与 CK和CK— MB两项酶学指标相比较。结果 :AMI组 ,c Tn T、CK及 CK— MB三者之间的异常率无明显差别 (异常率 97%～ 10 0 % ) ;而AP组 ,c Tn T的异常率为 44 .7% ,明显高于 CK异常率的 7.9%和 CK— MB异常率的 13.2 %。与健康组相比 ,AP组的 c Tn T测定的水平明显高于对照组水平 (P<0 .0 1)。结论 :对于不同程度的急性缺血性心肌损伤的诊断 ,c Tn T较 CK及 CK— MB,具有更高的灵敏度及特异性。
Objective: In order to early, accurately determine the degree of acute ischemic myocardial injury. Methods: Serum cardiac troponin T (cTn T) was measured in 41 patients with acute myocardial infarction, 38 patients with suspected myocardial damage (MMD) with angina pectoris (AP) and 40 healthy persons (HP) by enzyme-linked immunosorbent assay ) Determination, at the same time with CK and CK-MB two enzymatic indicators compared. Results: The abnormal rates of AMT, cTnT, CK and CK-MB had no significant difference (abnormal rate 97% -100%), but the abnormal rate of cTn T in AP was 44.7% , Significantly higher than 7.9% of CK abnormal rate and 13.2% of CK-MB abnormal rate. Compared with the healthy group, the level of cTn T in AP group was significantly higher than that in control group (P <0.01). Conclusion: For different degrees of diagnosis of acute ischemic myocardial injury, cTn T has higher sensitivity and specificity than CK and CK-MB.