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目的探讨急性脑梗死患者应用CT脑灌注与血管造影的效果。方法应用多层螺旋CT对收治的50例急性脑缺血患者进行灌注成像及血管造影检查,分析重建成像,计算并比较缺血区脑血流参数和对侧相应区灌注参数。结果 CT脑灌注成像检查中发现灌注异常区,血流量及脑血容量均有明显降低,对比剂平均通过时间及对比剂峰值时间均有明显延迟,与对侧比较差异显著(P<0.01),脑血容量与对侧比较差异无统计学意义(P>0.01),血管造影影像重建中26例患者一侧颈内动脉狭窄,10例患者一侧大脑中动脉狭窄,8例患者左侧大脑中动脉闭塞,6例患者左侧颈内动脉闭塞。结论 CT脑灌注可以及时准确的显示患者的缺血部位和程度,血管造影可以清晰显示血管病变的位置和程度,联合应用两种诊断方法可以提高急性脑梗死患者的诊断准确率。
Objective To investigate the effect of CT cerebral perfusion and angiography in patients with acute cerebral infarction. Methods 50 cases of acute cerebral ischemia treated with multi-slice spiral CT were examined by perfusion imaging and angiography. Reconstruction and imaging were performed. Cerebral blood flow parameters in ischemic area and perfusion parameters in contralateral area were calculated and compared. Results CT perfusion imaging revealed a significant decrease in perfusion area, blood flow and volume of cerebral blood flow. The mean contrast-up time and peak contrast time were significantly delayed compared with contralateral (P <0.01) There was no significant difference in cerebral blood volume between the two groups (P> 0.01). One of the 26 patients had stenosis of internal carotid artery in angiography reconstruction, the middle cerebral artery stenosis in 10 patients and the left brain in 8 patients Artery occlusion, left carotid artery occlusion in 6 patients. Conclusion CT perfusion can display the location and extent of ischemia in time. Angiography can clearly show the location and degree of vascular lesion. The combination of two diagnostic methods can improve the diagnostic accuracy of patients with acute cerebral infarction.