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目的 :讨论儿童及青春期垂体腺瘤的临床特点和治疗选择。方法 :回顾分析经手术及病理证实的儿童及青春期垂体瘤 2 3例 ,其中激素分泌性瘤 17例 ,无分泌瘤 6例。结果 :主要临床表现为内分泌障碍 (83 % ) ,头痛 (61% )和视路改变 (43 % )。肿瘤获大部和全切除 2 1例。 12例平均随访 5 3个月 ,7例作过放疗 ,11例已工作或上学。结论 :儿童及青春期垂体瘤以激素分泌性瘤和大腺瘤为主 ,临床除有成年人垂体瘤的表现外 ,尚有生长迟缓 ,原发闭经的特点。以手术治疗为主 ,肿瘤残留者术后给予低剂量放疗
Objective: To discuss the clinical features and treatment options of children and adolescent pituitary adenomas. Methods: A retrospective analysis of 23 cases of children and adolescent pituitary tumors confirmed by surgery and pathology, including 17 cases of hormone secreting tumors and 6 cases of non-secreting tumors. Results: The main clinical manifestations were endocrine disorders (83%), headache (61%) and visual pathway changes (43%). Most of the tumor and total resection 21 cases. Twelve patients were followed up for an average of 53 months, 7 were treated with radiotherapy, and 11 had been working or attended school. Conclusion: Pituitary adenomas in children and adolescents are mainly hormone secreting tumors and large adenomas. In addition to the clinical manifestations of pituitary adenomas in adults, there are still some characteristics of slow growth and primary amenorrhea. Surgical treatment, residual tumor were given low-dose radiotherapy