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相比结肠癌,过去人们认为直肠癌的生存率更低。目前,已有随机试验证明直肠癌的局部复发率有改善,而生存率的改善尚未被证实。为了证明直肠癌的生存率相对结肠癌有了提高,Renouf DJ等人分别比较了1989~1990年和2001~2002年2个时间段内375例和1 052例Ⅱ/Ⅲ期结直肠癌患者的治疗方案、疾病特异性生存率(disease-specific survival,DSS)和患者整体生存率(overall survival,OS)。结果发现:围手术期化疗在结直肠癌治疗中的应用明显增多(P<0.001),围手术期放
Compared to colon cancer, in the past people think that the survival rate of rectal cancer is lower. At present, there have been randomized trials to prove that the local recurrence rate of rectal cancer has improved, and the improvement of the survival rate has not been confirmed. In order to prove that the survival rate of rectal cancer relative to colon cancer has increased, Renouf DJ et al were compared 375 cases and 1 052 patients with stage Ⅱ / Ⅲ colorectal cancer in two periods of 1989 ~ 1990 and 2001 ~ 2002 Treatment regimen, disease-specific survival (DSS), and overall survival (OS). The results showed that: perioperative chemotherapy in the treatment of colorectal cancer was significantly increased (P <0.001), perioperative release