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通过检测胎盘合成物质在孕妇血、尿中的含量,以间接了解胎盘的功能,协助预测胎儿的安危,已成为近代对高危妊娠的一项重要监护措施。胎盘分泌多种激素、酶及合成一些功能尚不十分明确的蛋白,经过大量的研究和筛选,目前认为对胎儿眙盘有意义的生化监测项目并不多,主要有雌三醇(E_3)、胎盘泌乳素(hPL)、耐热碱性磷酸酶(HSAP)、妊娠特异β_1球蛋白(SP_1)、胎盘蛋白5(PP_(?))等,其中最广泛应用的是雌三醇(E_3)。应当指出,任何一项生化监测方法都有较高的假阳性率及假阴性率,所以有人主张数种项目联合应用,如E_3+hPL,E_3+
It has become an important monitoring measure for high-risk pregnancies in modern times by detecting the content of placenta synthetic substances in the blood and urine of pregnant women and indirectly understanding the function of the placenta to help predict the safety of the fetus. Placental secretion of a variety of hormones, enzymes and the synthesis of some features are not yet very clear protein, after a lot of research and screening, the current view of the fetus pan meaningful biochemical monitoring project is not much, mainly estriol (E_3) Placental prolactin (hPL), heat resistant alkaline phosphatase (HSAP), pregnancy specific β_1 globulin (SP_1), placenta protein 5 (PP_ (?)) And so on, the most widely used is estriol (E_3). It should be noted that any biochemical monitoring method has a higher false positive rate and false negative rate, so some people advocate the joint use of several projects, such as E_3 + hPL, E_3 +