论文部分内容阅读
目的:研究熏洗一号方在伤口愈合中的作用机制。方法:以熏洗一号方、洁尔阴、PP粉、生理盐水分别熏洗小鼠实验性肛旁手术伤口,通过观察各组小鼠术后第5天伤口上皮爬行及肉芽组织出现情况、术后7、14天伤口抗张强度、术后5、9、13天伤口愈合率和平均愈合天数来判断药物对伤口愈合作用的影响。结果:熏洗一号方能促进上皮爬行的出现,术后7、14天伤口抗张强度明显提高,术后9、13天伤口愈合率提高,平均愈合天数提前。洁尔阴能使术后14天伤口抗张强度提高,第13天伤口愈合率提高。PP粉组各指标与生理盐水组无显著性差异。结论:说明熏洗一号方有促进伤口愈合的作用。
Objective: To study the mechanism of fumigating No. 1 in wound healing. METHODS: The experimental perianal surgical wounds were fumigated with fumigant No.1, Jieyinyin, PP powder and physiological saline, and the wound epithelial crawling and appearance of granulation tissue were observed on the fifth day after operation in each group of mice. The influence of drugs on wound healing was evaluated by the wound tensile strength at 7, 14 days after surgery, the wound healing rate at 5, 9 and 13 days and the average healing days. RESULTS: Fumigating No. 1 could promote the appearance of epithelial crawling. The wound tensile strength was significantly improved on the 7th and 14th days after operation. The wound healing rate was improved on the 9th and 13th days after operation, and the average healing days were advanced. Jieer Yin can increase the tensile strength of wounds 14 days after surgery, and increase the wound healing rate on the 13th day. There was no significant difference between the PP powder group and the saline group. Conclusion: It is indicated that Fumigao No. 1 can promote wound healing.