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目的 探讨血清总唾液酸 (TSA)和脂结合唾液酸 (LSA)含量对口腔颌面部恶性肿瘤的诊断意义。方法 采用化学比色法同步检测了口腔颌面部恶性肿瘤患者TSA和LSA含量 ,并与健康对照组和口腔颌面部良性肿瘤组进行了对比分析。结果 口腔颌面部恶性肿瘤组血清TSA和LSA含量均明显高于健康对照组和良性肿瘤组 (P <0 .0 1) ,而健康对照组与良性肿瘤组之间血清TSA和LSA均无统计学意义 (P >0 .0 5 )。结论 血清TSA和LSA含量检测作为恶性肿瘤诊断的标志物 ,对口腔颌面部恶性肿瘤的诊断及鉴别诊断均具有一定的价值
Objective To investigate the diagnostic value of serum total sialic acid (TSA) and lipid-bound sialic acid (LSA) in oral and maxillofacial malignancies. Methods The contents of TSA and LSA in oral and maxillofacial malignant tumors were simultaneously detected by chemical colorimetry, and compared with the healthy control group and oral and maxillofacial benign tumor group. Results The levels of serum TSA and LSA in oral and maxillofacial malignant tumor group were significantly higher than those in healthy control group and benign tumor group (P <0.01), but there was no statistical significance between TSA and LSA in healthy control group and benign tumor group Significance of learning (P> 0.05). Conclusion Serum TSA and LSA levels are useful markers in the diagnosis of malignant tumors of the oral and maxillofacial region as diagnostic markers for differential diagnosis of malignant tumors