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探讨抑制脂肪酸合成酶对人乳腺癌和大肠癌细胞生长的影响及其可能的作用机制。体外实验中应用 MTT法观察抑制脂肪酸合成酶对细胞生长的影响 ,并通过流式细胞仪对细胞周期变化及细胞凋亡进行检测。结果 :脂肪酸合成酶抑制剂 Cerulenin可抑制人乳腺癌和大肠癌细胞生长 ,并诱导细
To investigate the effect of inhibition of fatty acid synthase on the growth of human breast and colorectal cancer cells and its possible mechanism. MTT assay was used to observe the effect of inhibiting fatty acid synthase on cell growth in vitro, and cell cycle changes and apoptosis were detected by flow cytometry. Results : The fatty acid synthase inhibitor Cerulenin inhibited the growth of human breast and colorectal cancer cells and induced fine