当手术时或手术短时间后,由于损伤组织产生血纤维蛋白溶解酶及其激活剂致纤维蛋白原遭受破坏而发生严重出血。此种病人于手术前检查出血时间、凝血时间和血小板总数可以正常。其正常凝血机构完全无损,惟其凝血块随时形成随时崩裂。一个14岁的男孩,因二尖瓣狭窄进行连合部切开术。于此患者血液中加入纤维蛋白后形成的凝血块,于加入该患者血清 Severe bleeding occurs when or shortly after surgery due to destruction of fibrinogen due to fibrinolytic enzymes and their activators produced by the injured tissue. Such patients check bleeding time before surgery, clotting time and the total number of platelets can be normal. The normal coagulation mechanism is completely nondestructive, but its clot formation at any time cracked at any time. A 14-year-old boy who underwent mitral suturing due to mitral stenosis. In this patient’s blood coagulation clot formed after the addition of fibrin, added to the patient’s serum