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为了对化学性胸膜粘连术(CP)提供有效 药物的资料,作者搜集1966~1992年间关于恶性胸腔积液(MPE)治疗的英文医学文献。从每篇文献中摘取的资料包括CP的方案、治疗人数、有效率(完全有效)及不良反应。由于疗效的标准各异,作者把临床检查或胸片肯定胸腔积液无再积聚者定为完全有效。曾研究的药物包括强力霉素(DXC)、二甲胺四环素(minocy-cline,MNC)、四环素、博莱霉素、顺铂、阿霉素、鬼臼乙叉甙、氟尿嘧啶、干扰素-β、丝裂霉素-C、
In order to provide information on effective drugs for chemical pleural adhesion (CP), the authors collected English medical literature on the treatment of malignant pleural effusion (MPE) from 1966 to 1992. The data extracted from each of the literature included CP protocol, number of treatments, efficiency (completely effective), and adverse reactions. Because of the varying standards of efficacy, the authors determined that clinical examination or chest pleural effusion confirmation of no re-accumulation is completely effective. Drugs studied include doxycycline (DXC), minocy-cline (MNC), tetracycline, bleomycin, cisplatin, doxorubicin, etoposide, fluorouracil, interferon-β , Mitomycin-C,