本文介绍美国Texas儿童医院临床使用五种抗心律失常新药的经验,以探讨其应用价值。胺碘达隆酮治疗39例,年龄6周～30岁(中位数12.2岁),其中(心)房扑(动)16例,室(性心动过)速14例,室上(性心动过)速9例。口服给药:先给10mg/kg/d,共10天;继以5mg/kg/d,1～2个月。如心律失常控制满意,渐减量至每5～7天使用2.5mg/kg维持。其它抗心律失常药应该停用或者减量。以用药后与心律失常有关的症状消失,24小时Holter心电图检查无心律失常复发至少6个月作为胺碘达隆洽疗有效。治疗结果:房扑有效率94％,室速有效率79％,室上速有效率78％。疗效一般在治疗4天后开始出现,较成人为早。副作用发生率28％,包括 This article describes the clinical use of five anti-arrhythmic drugs in Texas Children’s Hospital clinical experience to explore its value. Amiodarone was given to 39 patients aged 6 weeks to 30 years (median 12.2 years). Among them, 16 were atrial flutter (heart), 14 were supraventricular (tachycardia), and supraventricular Too fast) in 9 cases. Oral administration: give 10mg / kg / d for 10 days; followed by 5mg / kg / d, 1 to 2 months. Such as arrhythmia control satisfaction, decreasing to every 5 to 7 days with 2.5mg / kg maintenance. Other antiarrhythmic drugs should be disabled or reduced. After treatment with arrhythmia-related symptoms disappear, 24-hour Holter ECG without arrhythmia recurrence of at least 6 months as amiodarone treatment of effective. Treatment outcome: atrial flutter efficiency of 94%, 79% effective room velocity, supraventricular tachycardia effective rate of 78%. Efficacy generally began to appear after 4 days of treatment, as early as adults. The incidence of side effects 28%, including