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目的 观察并分析研究肝癌患者脾脏T细胞亚群的免疫状态.方法 取我院2014G6-2016G10就诊的54例肝癌患者为观察组,54例来我院健康体检的正常者为对照组,检测免疫功能相关指标.结果 对比两组成员,观察组CD4+、CD4+/CD8+水平下降显著,CD8+水平有所上升,ILG2、IFNGγ、ILG12水平上升明显(P<005).结论 肝癌患者通过检测脾脏T细胞亚群得到结论,细胞免疫功能明显被抑制,大幅度降低了机体免疫系统清除肿瘤的能力,也为临床增强免疫功能的治疗提供理论依据.
Objective To observe and analyze the immune status of T lymphocyte subsets in spleen of patients with hepatocellular carcinoma.Methods Totally 54 patients with hepatocellular carcinoma treated in our hospital 2014G6-2016G10 were selected as the observation group and 54 healthy controls were selected as the control group.The immune function (P <0.05) .Conclusion Compared with the two groups, the levels of CD4 + and CD4 + / CD8 + in the observation group decreased significantly, while the level of CD8 + increased and the levels of ILG2, IFNGγ and ILG12 increased significantly It is concluded that the cellular immune function is significantly inhibited, which greatly reduces the ability of the immune system to clear the tumor and provides a theoretical basis for the clinical treatment of enhancing immune function.