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本文采用诺氟沙星治疗30例伤寒患者,致病菌均耐氯霉素等多种抗生素。20例单用诺氟沙星治疗,19例治愈。10例用氯霉素、氨苄西林、阿米卡星、庆大霉素、美西林和SMZ-CO治疗5-11 d无效,其中4例改用诺氟沙星,6例选上述抗生素1-3种合并诺氟沙星后治愈。诺氟沙星剂量为0.4g,每日4次,口服,体温正常后继服2wk,平均退热时间5.2 d。本药副作用轻微,病人能耐受,故认为诺氟沙星可推荐治疗耐多种抗生素的伤寒的首选药物。
This article uses norfloxacin in 30 typhoid patients, pathogens are resistant to chloramphenicol and other antibiotics. 20 cases were treated with norfloxacin alone and 19 cases were cured. 10 cases with chloramphenicol, ampicillin, amikacin, gentamicin, mecillin and SMZ-CO treatment 5-11 d ineffective, of which 4 were converted to norfloxacin, 6 patients selected antibiotics 1- Three kinds of norfloxacin after the merger cured. Norfloxacin dose of 0.4g, 4 times a day, oral, body temperature normal follow-up service 2wk, the average antipyretic time 5.2 d. The drug has mild side effects, the patient can tolerate, so that norfloxacin can be recommended for the treatment of typhoid resistant to multiple antibiotics drug of choice.