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目的研究B型钠尿肽(BNP)在妊娠期高血压疾病患者中的水平变化和对评估患者并发心力衰竭的意义。方法 232例妊娠期高血压疾病患者,分为妊娠期高血压76例(A组),轻度子痫前期64例(B组),重度子痫前期89例(C组),并发心力衰竭重度子痫前期3例(D组)。监测各组BNP水平及血压变化,分析BNP水平与心功能的关系。结果随着患者血压升高BNP水平也逐渐升高,C、D两组BNP水平与A、B两组比较,差异有统计学意义(P<0.05)。结论监测妊娠期高血压疾病患者血浆BNP水平对于评价妊娠期高血压疾病病情及评估心功能有一定临床意义。
Objective To study the changes of levels of B-type natriuretic peptide (BNP) in patients with hypertensive disorders of pregnancy and its significance in assessing patients with heart failure. Methods A total of 232 cases of hypertensive disorders of pregnancy were divided into 76 cases of pregnancy-induced hypertension (group A), 64 cases of mild preeclampsia (group B) and 89 cases of severe preeclampsia (group C) with severe heart failure 3 cases of preeclampsia (group D). The levels of BNP and blood pressure in each group were monitored, and the relationship between BNP level and cardiac function was analyzed. Results The level of BNP increased with the increase of blood pressure. There was significant difference in BNP level between groups C and D and groups A and B (P <0.05). Conclusion Monitoring plasma BNP level in patients with hypertensive disorder complicating pregnancy has some clinical significance for evaluating the condition of hypertensive disorder complicating pregnancy and assessing cardiac function.