由于抗生素、皮质激素及免疫抑制剂的广泛应用等多种因素的影响 ,给条件致病真菌创造感染的机会 ,耳鼻咽喉真菌病(ENTM)的报道与日剧增[1～ 2 0 ] ,致病真菌耐药性的产生 ,真菌与细菌的混合感染而顽固难愈 ,侵袭型病变给患者生命造成严重威胁 ,这是困扰医者的一个棘手难题。ENT Due to the wide range of applications of antibiotics, corticosteroids and immunosuppressive agents and other factors, the opportunity to create opportunistic pathogenic fungi, the ENTM reported and the Japanese surge [1 ~ 20], resulting in Pathogenic fungal drug resistance, fungal and bacterial mixed infection and stubborn refractory, invasive lesions pose a serious threat to the lives of patients, which is plagued by doctors a difficult problem. ENT